Cervical cancer is the fourth most common cancer among women globally and currently, one life is lost every two minutes to this disease.
Cervical cancer ranks fourth of all cancers and currently, it is the highest cause of cancer deaths in women in 38 countries.
In 2022, more than 348,000 women died from cervical cancer worldwide and this number is likely to continue to grow, particularly in underprivileged and vulnerable communities. Current data suggests that 90% of all cases occur in low- and middle-income countries, due largely to poor access to screening and early detection and treatment of both pre-cancers and cancer.
However, cervical cancer is one of the most preventable and successfully treatable forms of cancer, if it is detected and diagnosed early, and managed effectively. Like many cancers, the earlier cervical cancer is detected, the higher the chances are of survival.
In this episode of Let’s talk cancer, Dr Chemtai Mungo from the University of North Carolina, and UICC Young Leader 2021/22 explains the challenges and advances in cervical cancer care and improving access to life-saving services for all populations.
Cervical cancer is the uncontrolled growth of abnormal cells in the lining of the cervix. The cervix is part of the female reproductive system and is located in the lower part of the womb, forming the opening from the womb to the vagina.
Most cervical cancers are caused by human papillomavirus (HPV) infections. HPV is a group of viruses that are extremely common worldwide. There are more than 100 types of HPV, of which at least 14 are cancer-causing (also known as high-risk types). Two HPV types (16 and 18) cause 70% of cervical cancers and pre-cancerous cervical lesions. There is also evidence linking HPV with cancers of the anus, vulva, vagina, penis and oropharynx. (WHO cervical cancer fact sheet)
There are two main types of cancer of the cervix: squamous cell carcinomas (about 80-90% of cervical cancers) and adenocarcinomas (about 10-20% of cervical cancers).
Diagramme showing stage 1B cervical cancerAuthor: Cancer Research UK - CC BY-SA 4.0
Following the call to action in 2018 by the World Health Organization Director General, Dr Tedros Adhanom Ghebreyesus, in 2020, the World Health Assembly passed a resolution, and adopted a strategy aimed at eliminating cervical cancer worldwide as a public health problem.
The Global Strategy identifies the following threshold: cervical cancer would no longer be considered to be a public health problem when all countries reach an annual incidence rate of four cases per 100,000 women or less.
Elimination of cervical cancer could happen within the lifetime of today’s young girls.
The Global Strategy outlines three main pillars to achieving this goal requiring accelerated action in prevention, screening and cancer management, to reach the following targets by 2030:
of girls fully vaccinated with HPV vaccine by 15 years of age
of women are screened with a high-performance test by 35 and 45 years of age, pre-cancerous lesions are treated early
of women identified with cervical disease receive treatment (including treatment of cervical pre-cancer, and invasive cancer)
In order to achieve elimination, action across all three pillars is critical. No single intervention is enough.
It is estimated that achieving and sustaining the 90:70:90 targets will avert 74 million new cases of cervical cancer and 62 million deaths in 78 low- and middle-income countries by 2120.
17 November marks the Cervical Cancer Elimination Day of Action and the anniversary of the launch of the World Health Organization’s (WHO) Global Strategy to accelerate the elimination of cervical cancer as a public health problem.
The Global Strategy and its related targets represent a unique opportunity to drive long-term, sustainable advocacy and save lives.
Access National Cervical Cancer Plans
Following the call to action in 2018, UICC directly supported WHO’s efforts to conceive, draft and present the Global Strategy to accelerate the elimination of cervical cancer as a public health problem, which was launched on 17 November 2020.
Since then, UICC has been part of the WHO-led Cervical Cancer Elimination initiative, committed to supporting and working with its diverse and global membership to assist countries in achieving the 90:70:90 targets for vaccination, screening and treatment, and continuing to maintain a spotlight on cervical cancer elimination, leveraging its global platforms and harness its convening role across sectors to drive global impact.
In fulfilment of these commitments, UICC is delivering and provides a series of activities, opportunities and projects, working with partners, members and organisations around the world to support collective progress towards the 2030 targets.
Learn more about UICC's actions on cervical cancer
Learn more about the strategy and download it here
View more resources
UICC works closely with the World Health Organization (WHO), other UN agencies and partners towards the elimination of cervical cancer as a public health problem.
This page regroups important resources such as infographics, videos, documents and links related to cervical cancer elimination.
The ICCP Portal features additional resources on cervical cancer prevention and control such as National Cervical Cancer Control Strategies and Plans.
In 2020, the WHO set the 90-70-90 targets aiming to eliminate cervical cancer by 2030. Vaccinate 90% of girls, screen 70% of women, treat 90% with cervical disease. Expected benefits include a 42% reduction in cervical cancer rates by 2045 and preventing over 74 million new cases by 2120, with 300,000 deaths averted by 2030.
UICC analysed the role of civil society organisation (CSOs) in promoting HPV vaccination for cervical cancer elimination, identified barriers, and launched the summary on the Global Strategy's third anniversary.
Share this page